Clarissa Brincat

All articles by Clarissa Brincat

• Structured exercise programs may help people with ATTR-CM

  Structured exercise can improve strength and quality of life in people with ATTR-CM, according to a recent review.

• ATTR-CM treatment options are growing, but more research is needed

  New therapies have greatly expanded the options for treating ATTR-CM, but more research is needed on therapies that remove amyloid deposits.

• Research suggests people with ATTR-CM need support for anxiety and depression

  People living with ATTR-CM often experience high levels of anxiety and depression that have an impact on their physical health.

• p.V142I TTR gene variant raises risk of heart problems in carriers over 50

  People with the p.V142I variant, linked to hATTR-CM, are more likely to develop heart failure and atrial fibrillation starting in their 50s.

• AI tools could lead to earlier ATTR-CM diagnosis, with no racial bias

  AI tools could help doctors to detect transthyretin amyloid cardiomyopathy (ATTR-CM) earlier and more fairly across different racial groups.

• Tafamidis shows promise for mixed-phenotype ATTR-CM

  Tafamidis helps people with mixed-phenotype ATTR-CM live longer with fewer heart-related hospitalizations and deaths.

• What is Donegal Amy?

  About one in 100 people in Donegal, Ireland, may have the genetic variant for this form of hereditary ATTR.

• Nerve symptoms in ATTR-CM may signal higher risk of heart complications

  For patients with ATTR-CM, nerve symptoms — known as autonomic dysfunction — could be a warning sign of more serious heart trouble ahead.

• What to know before a cardiac PYP scan to diagnose ATTR-CM

  You’ll need to hold still for about 30 minutes.

• Blood flow may drive ATTR-CM by causing TTR proteins to clump

  The physical force of blood flow may contribute to the development of transthyretin amyloid cardiomyopathy (ATTR-CM).