Gut bacteria linked to heart and digestive symptoms in ATTR-CM
Understanding how bacteria interact with heart and digestive health could lead to more personalized treatments for patients with ATTR.
Understanding how bacteria interact with heart and digestive health could lead to more personalized treatments for patients with ATTR.
A patient with transthyretin amyloid cardiomyopathy (ATTR-CM) benefited from early diagnosis and treatment with an oral transthyretin stabilizer, according to a case report published recently in Cureus. The 67-year-old man experienced lessening symptoms of heart failure after starting on the stabilizer. Despite worsening shortness of breath, swelling in his legs and reduced exercise tolerance, he […]
ATTR-CM is being diagnosed more frequently because of improved awareness and diagnostic tools, making it more common than previously thought.
The European Commission approved acoramidis to treat adults with wild-type or variant ATTR-CM in the European Union.
Despite treatment advancements, ATTR remains poorly understood, with significant variations in prevalence and survival rates across regions.
Emerging therapies — including TTR stabilizers, silencers and depleters — offer new hope for managing ATTR-CM.
Advances in radionuclide imaging and emerging therapies have improved diagnosis and management of ATTR-CM.
Treatment advances such as RNA silencing and gene-editing technologies offer hope to improve outcomes for patients with ATTR-CM.
Minimal versatile genetic perturbation technology showed promise in addressing genetic diseases such as ATTR-CM.
Older patients faced a higher prevalence of coexisting cardiac amyloidosis, including ATTR-CM, and coronary artery disease.